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Joe Manniello

Joe Manniello's Week 10 NFL picks

If you're a Giants fan who finds yourself flipping back and forth between Big Blue and NFL Red Zone on most Sundays, Week 10 will be the rare exception. There are only five 1 p.m. games, and the other four are nothing special. The 4 p.m. slate features a whopping six games, including some interesting matchups.

Underdogs continued to bark last week, as favorites went 5-9 against the spread (ATS) after going 4-10 the previous week. Favorites have now dipped to 56-72-2 for the season. Home teams went 5-9 straight up and 7-7 ATS, bringing their totals to 65-67-1 and 59-72-2.

My three most confident picks this week are Miami, the L.A. Rams and Baltimore. Avoid Buffalo-Arizona, a great game but a difficult one to handicap.

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