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LiveScience
LiveScience
Emily Cooke

Is it too late to get a flu shot?

Person wearing a blue face mask sits and watches a nurse who is preparing their arm for vaccination.

Each year, as fall brings shorter, colder days to the Northern Hemisphere, we're reminded to get vaccinated against the flu, or influenza. In the U.S., the Centers for Disease Control and Prevention (CDC) recommends that everyone over 6 months old receive a flu shot every year. 

But is there a time limit on getting your flu shot? While it's best to get vaccinated before the season kicks off in earnest, it's still beneficial to get one toward the end of the season, two infectious-disease experts told Live Science.

Related: Never-before-seen antibodies can target many flu viruses

Normally, flu vaccines become available in late summer. Specific groups, such as pregnant people in their third trimesters, might consider vaccination in the summer. But the CDC recommends that most eligible people get vaccinated in the fall, by the end of October, as this is when cases begin to rise. 

"In the U.S., we often say to get vaccinated around October, because that's when cases start going up and we know that the flu vaccine gives you good protection over a certain period of time," Dr. Sabrina Assoumou, an associate professor of medicine at Boston University and an attending physician at Boston Medical Center, told Live Science. 

But if you miss that time window for some reason, you should still get a flu shot.

"Flu season typically continues through March, and it generally takes about two weeks after getting a flu shot for immunity to start kicking in," Dr. Daniel Kuritzkes, chief of the Division of Infectious Diseases at Brigham and Women's Hospital in Boston, told Live Science in an email. So, if you haven't been vaccinated yet, it still makes sense to do so through the end of February, and maybe even into early March, he said. 

There would also be "no harm" in getting vaccinated after March or April, considering that influenza viruses circulate all year round, Kuritzkes said. However, practically speaking, the risk of catching flu in the spring or summer is "so low" that healthcare professionals don't generally focus on vaccinations once flu season is over, he said. 

If you haven't gotten sick by January, it may be tempting to think, "Oh, the holidays are done; I've dodged a bullet," Assoumou said. However, cases can still be seen later in flu season, and the later you get vaccinated, the shorter your window of available protection for that particular flu season, Assoumou added. 

Notably, the peak of flu season has been difficult to predict in recent years due to COVID-19. 

Flu transmission most often peaks in February in the U.S. — but the COVID-19 pandemic temporarily disrupted the timing of this. For instance, in 2020, flu transmission reached historically low levels. Between 2021 and 2022, flu infections began to rise again, peaking in late December 2021 then again in April 2022, but transmission rates stayed high until mid-June. However, between 2022 and 2023, transmission peaked in late November and early December

This suggests that "we're moving back towards more typical patterns in terms of influenza epidemiology," Kuritzkes said. Therefore, getting a flu shot in the fall continues to make the most sense, he said. 

The flu vaccine protects against the strains of influenza virus (illustrated above) predicted to be most prevalent in a given season. (Image credit: KATERYNA KON/SCIENCE PHOTO LIBRARY via Getty Images)

But what if you've already had the flu this season? Is it still worth getting vaccinated afterward?

Although it may seem counterintuitive, experts say yes. That's because many strains of influenza circulate each year. These strains fall into two broad categories — influenza A and influenza B — that are responsible for seasonal epidemics of the disease. 

"For reasons we don't fully understand, in a typical year the majority of cases seen early in flu season tend to be influenza A, whereas cases due to influenza B are more common later in the season," in February and March, Kuritzkes said. 

"Therefore, an unvaccinated person who gets flu in December or January from one type of influenza could still be susceptible to catching flu again later in the season from the other type," he said. 

The annual flu vaccine is designed to provide protection against the major strains of influenza that are expected to circulate in that particular season. Flu vaccines in the U.S. are "quadrivalent," meaning they protect against four strains. 

And even if you still get the flu after being vaccinated, you're much less likely to develop a severe infection or to be hospitalized, Assoumou said. "The role of these vaccines is to convert a severe infection into a mild one," she said. 

People often forget just how deadly the flu can be, so it is really important that everyone gets vaccinated, Assoumou said. This is especially true for people who are at a heightened risk of flu complications, such as those who are pregnant, over age 65 or have underlying chronic health conditions, such as asthma or heart disease, according to the CDC. 

Getting the flu vaccine is the "best way to protect yourself and the community" regardless of when you receive it, Assoumou said. 

This article is for informational purposes only and is not meant to offer medical advice.

Ever wonder why some people build muscle more easily than others or why freckles come out in the sun? Send us your questions about how the human body works to community@livescience.com with the subject line "Health Desk Q," and you may see your question answered on the website!

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