Children have reportedly been trapped under the wreckage after the Russian bombing of a maternity hospital in the Ukrainian city of Mariupol, the country's president Volodymyr Zelensky has said.
He shared harrowing footage of the aftermath of the ruthless bombing of the facility with early indications suggesting 17 people have been wounded by the attack.
Members of staff and women in labour were among those wounded, officials say.
The cameraman is forced to pick their way through the remains, and what's left of flowers can be seen on tables, as walls have been blown out and windows destroyed.
Tweeting out the video, Zelensky once again called out Russian atrocities as they continue a barbaric campaign targeting civilians and the vulnerable left in warn-torn Ukraine.
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He said: "Mariupol. Direct strike of Russian troops at the maternity hospital. People, children are under the wreckage. Atrocity!
"How much longer will the world be an accomplice ignoring terror? Close the sky right now! Stop the killings! You have power but you seem to be losing humanity."
The clip shows one building totally destroyed and another badly damaged as wounded patients swiftly evacuate.
Children are reportedly buried under rubble after the Russian airstrike but it was not immediately clear whether there were any casualties.
Prime Minister Boris Johnson tweeted: "There are few things more depraved than targeting the vulnerable and defenceless. The UK is exploring more support for Ukraine to defend against airstrikes and we will hold Putin to account for his terrible crimes."
Mariupol city council earlier said in a Facebook post that a children’s hospital had been destroyed.
"The destruction is colossal," the post read. "The building of the medical facility where the children were treated recently is completely destroyed. Information on casualties is being clarified."
The battered port city's deputy mayor Serhiy Orlov, told the BBC: "We don't understand how it is possible in modern life to bomb children's hospital."
He says people in Mariupol who managed to escape the hospital are in "total anger" and "cannot believe it is true".
Liz Truss called Russia's attack on maternity and children's hospital 'abhorrent, reckless and appalling'.
But the Foreign Secretary ruled out a no fly zone in response to Zelensky's calls, saying the best way to 'protect the skies' is to continue to supply aid to Ukraine.
Hours earlier, Ukrainian foreign minister Dmytro Kuleba said that 3,000 babies were without food or medicine.
He said the infants could die and begged for for a humanitarian corridor to allow them to leave.
At least 516 civilians have been killed since Russia began its invasion on February 24, the UN human rights office has said.
Bodies heartbreakingly lie scattered in the streets of Mariupol as Russia continues to bombard the besieged Ukrainian city.
The Red Cross say the humanitarian crisis in Mariupol is 'apocalyptic' and worsening by the hour.
Hundreds of thousands of residents have been forced to shelter for nearly ten days without water or power.
Now experts say we are we starting to see the full impact of Russia's deadly invasion.
In what has been called a vision of the future for every city in the war-torn country, the dead are left abandoned more than a week after fighting broke out.
Red Cross spokeswoman Ewan Watson said: "This situation is really apocalyptic for people, it is getting worse, they are running out of essential supplies.
“We’ve depleted our stocks. As I said, it stands to reason that people are coming to the end of whatever supplies they had.”
Today, Mariupol City Council say another Russian bombing has completely destroyed a children's hospital in the city.
More than 2 million refugees have fled their homes into neighbouring countries after Vladimir Putin launched his invasion 14 days ago.
Ukraine will continue its attempt to evacuate civilians along safe routes agreed with Moscow, the country’s deputy prime minister last night stated.
Iryna Vereshchuk confirmed Ukrainian forces would hold their fire during a 12-hour window from 9am until 9pm local time on Wednesday.
She appealed to Russian forces to stick to their “official public commitment” and do the same.
Authorities state the routes should allow civilians from Mariupol, Enerhodar, Sumy, Izyum and Volnovakha to leave.
Respected war author Tomi Ahonen says we are now starting to really see Putin's methods - the twisted butchering of civilians deliberately to flex his muscle.
He tweeted: "It is a cruel psychological warfare method, designed to crush hope. To defeat a NATION. Putin creates horrible pressure to the citizens of Mariupol. Then offers them hope. And then DESTROYS that hope. And repeat, and repeat, and repeat. Pure evil."
Later, he added: "Putin intends to do this to EVERY city he captures, crush all those people in the same way. If they get out alive, their psychological damage is likely to never be fixed.
"He is committing war crimes in front of our eyes, & he doesn't care."
It comes after a girl, six, died from dehydration "alone, weak, frightened, thirsty" in Mariupol yesterday after spending days with no water, power, or heating supplies.
Ukrainian President Volodymyr Zelensky announced the child's death in a distressing video address and officials later said her name was Tanya.
