A student at a major Brisbane high school has tested positive to COVID-19, with no clear link as to how she contracted the virus.
The case is the only new community transmission of the virus in the past 24 hours, with authorities checking the result is not a false positive.
Health Minister Yvette D'Ath said the 17-year-old attends Indooroopilly State High School, which has been closed for 48 hours for a deep clean and contact tracing.
The teenager lives with her family of five at Taringa, in Brisbane's inner west.
Ms D'Ath said the girl had become unwell yesterday and was tested overnight.
She had been in the community for three days while infectious and at school for two days.
"At this point, we understand the family hasn't travelled anywhere," Ms D'Ath said.
"We're still to get genomic sequencing to find out what variant it is and also whether it's linked to any other cases in Queensland or Australia.
Chief Health Officer Jeannette Young said genomic sequencing results were due back later today.
"I'm struggling to understand how she's acquired it," she said.
Dr Young said the school was alerted just after midnight.
Contact tracers are also investigating how the student travelled to school and other interactions she might have had within the community.
"The school is being closed today so there can be cleaning ... and we can work out which students need to go into 14 days quarantine," Dr Young said.
The school has almost 2,500 students.
Premier Annastacia Palaszczuk said further tests were being done to ensure the case was not a false positive.
"We'll be double checking that," she told ABC Radio Brisbane.
"We are told there is no association with any international travel."
The Department of Education said it expects the school will open for students on Monday, depending on advice from health authorities.
Expo held at school last night
In an email to students and their families last night, Acting Executive Principal Derek Weeks said the school would close immediately after advice from the health department.
"We are continuing to liaise with public health authorities and our own department in relation to the latest developments and will act immediately on their advice should there be an identified need to do so," Mr Weeks wrote in the email.
"If you, or a member of your family, are feeling unwell or displaying symptoms of COVID-19, please consult your GP."
Indooroopilly State High School Parents and Citizens Association vice president, Tony Ellison, said he was glad the school was taking precautions.
He said he believed the day would be treated as a day off as there was no remote learning initiatives in place.
Alex, who has two daughters attending Indooroopilly State High said they were still in the dark as to whether they should isolate.
"It's inevitable I guess that a student is going to pick it up at some stage, but we just haven't heard anything,” she told ABC Radio Brisbane.
"Luckily, we work from home but we've got another daughter who has to go to work. We don't know [whether] she has to stay home."
The school held a subject selection expo last night that was attended by students and parents.
The University of Southern Queensland has closed its Springfield campus, south of Brisbane, until Monday after three staff visited the school for the expo.
The campus is undergoing deep cleaning.
A spokeswoman for the university said the campus had recorded no COVID-19 cases and the decision had been taken out of an "abundance of caution".
A Griffith University spokesperson said four of its staff also attended the expo and two had returned a vehicle to the university which was to be deep cleaned.
All four staff who were present at the expo are isolating at home awaiting advice from Queensland Health.
There was one other case of COVID-19, recorded overnight in hotel quarantine, taking the state's active cases to 43.
A University of Queensland (UQ) spokesperson said two of its staff members who attended the expo "have not been on campus today".
"The safety and wellbeing of our staff and students remains UQ's highest priority and we will continue to follow relevant health advice," the spokesperson said.
Backpackers hostel still under lockdown
In south-east Queensland, 11 local government areas are entering another week of mandatory mask wearing.
Two backpacker hostels are in lockdown in Brisbane city after a returned traveller, who had completed hotel quarantine, tested positive to the Alpha variant while staying there.
Dr Young said authorities were still working to manage the situation and were tracking down people who might have stayed at the hostel before the case was revealed.
"We know that in any particular outbreak, someone can get infected, not have symptoms and then spread the virus to someone else, which is why it's critically important that we all remain very, very cautious.
"I'm comfortable that we're doing what's needed, we will just have to see what happens over the next few days, remembering that's an Alpha variant.
"I wouldn't be surprised if we get cases in the next 10 days."