Last year's historic winner Minella Times heads the initial 107 entries for the 2022 Randox Grand National at Aintree Racecourse.
While dual winner Tiger Roll has also been given an entry despite now being a 12-year-old.
Henry De Bromhead's eight-year-old was partnered by Rachael Blackmore when scoring at Aintree last April – as the Tipperary-born rider became the first female jockey to win the world's greatest steeplechase.
READ MORE: Unprecedented demand for Aintree and Cheltenham Festival tickets
Trainer De Bromhead himself became the first to send out the winners of the big three championship contests at the Cheltenham Festival – the Champion Hurdle (Honeysuckle), Queen Mother Champion Chase (Put The Kettle On) and Cheltenham Gold Cup (Minella Indo) – as well as the Grand National in the same season.
And now they are eyeing repeat at the famous Liverpool track on April 9.
De Bromhead also has Chris's Dream, Eklat De Rire, Plan Of Attack and Poker Party entered, although last year's runner-up Balko De Flos is not as he is out with a season-ending injury.
The JP McManus-owned Minella Times is a general 20-1 chance with most bookmakers for his bid for more Grand National glory.
Last year's third home – the Ted Walsh-trained Any Second Now, another of the 12 entries owned by dual National winner McManus – is generally the 16-1 market leader with most firms, alongside recent Grade One Savills Chase winner Galvin – from the Gordon Elliott stable who have won the Grand National three times.
Minella Times, Any Second Now and Galvin are among the massive 53 entries from Ireland. Irish-trained horses have won four of the last five runnings of the Aintree marathon and last year the Emerald Isle had the first five home.
Cullentra House handler Elliott – who won the Grand National with Silver Birch (2007) and dual winner Tiger Roll (2018, 2019) – has the most entries of any trainer this year with 18.
Tiger Roll was denied a possible hat-trick bid in 2020 after the race was cancelled due to the coronvirus pandemic and owners Gigginstown House Stud decided not to run him in 2021.
Instead, he ran in the Grade One Betway Bowl and finished fourth to Clan Des Obeaux after he had won the cross-country chase at the Cheltenham Festival for a third time.
Tiger Roll has been well beaten on both his starts this season – although Red Rum did win his third Grand National at the same age of 12 in 1977 after being second the previous two years.
As well as Tiger Roll and Galvin, Elliott could saddle Irish Grand National runner-up Run Wild Fred, the talented Samcro, last year's fifth home Farclas and former Grade One winner Delta Work.
Fourth home last year was Burrows Saint, who is one of eight entries for the Irish champion trainer Willie Mullins who won the Grand National with Hedgehunter in 2005.
Burrows Saint is a 33-1 chance with William Hill and Unibet.
The highest-placed British-trained runner last year was the Dan Skelton-trained Blaklion and he is entered again.
Now a 13-year-old, he won the Becher Chase over the Grand National fences when trained by Nigel Twiston-Davies in 2016, having also been fourth in the big one the April before.
Dual National hero Twiston-Davies – who is the only trainer to have won all five races run over the big Aintree fences – has entered Rowland Meyrick Chase scorer Good Boy Bobby, who is a best-priced 40-1.
The Jonjo O'Neill-trained Cloth Cap, who was pulled up last April when sent off favourite, is entered again and will run in the colours of the late Trevor Hemmings – who won the National three times before he died at the end of last year.
Among others entered are the O'Neill-trained Easysland – a winner of the cross-country chase at Cheltenham in the past, recent Warwick Classic Chase victor Eclair Surf, Irish Grand National scorer Freewheelin Dylan and Scottish National winner Mighty Thunder.
Recent Becher Chase heroine Snow Leopardess, who is trained by Charlie Longsdon, could bid to become the first mare to win the race since Nickel Coin in 1951.
Snow Leopardess is a 33-1 chance with William Hill, Betfred and Unibet.
The first two home in the Ladbrokes Trophy, Cloudy Glen – also owned by the Exors of the late Trevor Hemming – and Fiddlerontheroof, are also entered as is the Brian Ellison-trained Windsor Avenue, who landed the Sky Bet Chase at Doncaster last Saturday.
Last year's Welsh National winner Secret Reprieve – for Welsh rained and Everton FC fan Evan Williams – is also entered having missed the cut for last year's race.
Richard Hobson’s Lord Du Mesnil – who is owned by a syndicate which includes Mike and Mandy Smith from Wirral – is a three-time Haydock Park winner.
He was pulled up in last year's Grand National but is entered again this time.
Another Merseyside-owned horse, the Twiston-Davies-trained The Hollow Ginge, is entered for the Liverpool-born John Neild's Ginge Army.
Leading trainer Nicky Henderson has never won the Grand National, but he has an intriguing entry in Chantry House, who gave owner McManus his 4,000th winner when landing the Grade Two Cotswold Chase at Cheltenham at the weekend. He won over the Mildmay fences at last season's Grand National meeting, but is likely to be aimed at the Cheltenham Gold Cup before any potential Aintree bid.
The weights – which will be framed by BHA handicapper Martin Greenwood – for the Grand National, are scheduled to be unveiled at the traditional ceremony in two weeks.
The event hasn’t been held since 2019 due to the coronavirus pandemic when St George’s Hall was the venue.
This year’s lunch – which sees trainers, owners, key racing personnel and the media in attendance – is set to be at the Rum Warehouse in the Titanic Hotel, Liverpool, on Tuesday, February 15.
For information regarding tickets for the Cheltenham Festival visit thejockeyclub.co.uk/Cheltenham and for the Randox Grand National Festival visit thejockeyclub.co.uk/Aintree.
Full list of 107 entries for the 2022 Randox Grand National Handicap Chase (Grade 3) 4m2f74y at Aintree Racecourse on Saturday, April 9 (5.15pm).
Total Prize Fund £1,000,000
Achille (FR) 12 Mrs Vida Bingham Venetia Williams
Agusta Gold (IRE) 9 Dr SP Fitzgerald Willie Mullins Ireland
Alpha des Obeaux (FR) 12 Gigginstown House Stud Gordon Elliott Ireland
Anibale Fly (FR) 12 Mr John P McManus Tony Martin Ireland
Any Second Now (IRE) 10 Mr John P McManus Ted Walsh Ireland
Assemble 8 Gigginstown House Stud Joseph O'Brien Ireland
Back On The Lash 8 Mr M Boothright Martin Keighley
Battleoverdoyen (IRE) 9 Gigginstown House Stud Gordon Elliott Ireland
Blaklion 13 Darren & Annaley Yates Dan Skelton
Brace Yourself (IRE) 9 Mrs Patricia Hunt Noel Meade Ireland
Braeside (IRE) 8 KTDA Racing Gordon Elliott Ireland
Brahma Bull (IRE) 11 Mrs S. Ricci Willie Mullins Ireland
Burrows Saint (FR) 9 Mrs S. Ricci Willie Mullins Ireland
Caribean Boy (FR) 8 Mr Simon Munir & Mr Isaac Souede Nicky Henderson
Chantry House (IRE) 8 Mr John P McManus Nicky Henderson
Chatham Street Lad (IRE) 10 Mr V Healy Michael Winters Ireland
Chris's Dream (IRE) 10 Robcour Henry de Bromhead Ireland
Class Conti (FR) 10 Mr Simon Munir/Mr Isaac Souede Willie Mullins Ireland
Cloth Cap (IRE) 10 Exors of the late Mr Trevor Hemmings Jonjo O'Neill
Cloudy Glen (IRE) 9 Exors of the late Mr Trevor Hemmings Venetia Williams
Coko Beach (FR) 7 Gigginstown House Stud Gordon Elliott Ireland
Commodore (FR) 10 Mrs C Watson & Mrs S Graham Venetia Williams
Conflated (IRE) 8 Gigginstown House Stud Gordon Elliott Ireland
Court Maid (IRE) 9 Rory F Larkin Thomas Mullins Ireland
Death Duty (IRE) 11 Gigginstown House Stud Gordon Elliott Ireland
Defi Bleu (FR) 9 Gigginstown House Stud Gordon Elliott Ireland
Definite Plan (IRE) 10 Mr James J Reilly Gordon Elliott Ireland
Deise Aba (IRE) 9 Exors of the late Mr Trevor Hemmings Philip Hobbs
Delta Work (FR) 9 Gigginstown House Stud Gordon Elliott Ireland
De Rasher Counter 10 Makin' Bacon Partnership Emma Lavelle
Didero Vallis (FR) 9 Normans, Ramsay, Tufnell & Bishop Venetia Williams
Dingo Dollar (IRE) 10 M Warren J Holmes R Kidner & J Wright Sandy Thomson
Discorama (FR) 9 Andrew Gemmell/Thomas Friel Paul Nolan Ireland
Discordantly (IRE) 8 The Odd Fellows Partnership Jessica Harrington Ireland
Domaine de L'Isle (FR) 9 12 Oaks Racing and Mr Ian Hutchins Sean Curran
Double Shuffle (IRE) 12 Crossed Fingers Partnership Tom George
Easysland (FR) 8 Mr John P McManus Jonjo O'Neill
Eclair Surf (FR) 8 Dominic Burke & Tim Syder Emma Lavelle
Eklat de Rire (FR) 8 Mr P Davies Henry de Bromhead Ireland
Elegant Escape (IRE) 10 Mr JP Romans Colin Tizzard
El Presente 9 Davies Pilkington Yarborough Brooke Kim Bailey
Enjoy d'Allen (FR) 8 Railway View Stud Partnership Ciaran Murphy Ireland
Escaria Ten (FR) 8 McNeill Family Gordon Elliott Ireland
Eurobot 8 Gigginstown House Stud Noel Meade Ireland
Farclas (FR) 8 Gigginstown House Stud Gordon Elliott Ireland
Fiddlerontheroof (IRE) 8 Taylor, Burley & O'Dwyer Colin Tizzard
Fortescue 8 Mr TFF Nixon Henry Daly
Franco de Port (FR) 7 Bruton Street V Willie Mullins Ireland
Freewheelin Dylan (IRE) 10 Miss Sheila Mangan Dermot Anthony McLoughlin Ireland
Full Back (FR) 7 Mr Ashley Head Gary Moore
Galvin (IRE) 8 Mr R. A. Bartlett Gordon Elliott Ireland
Go Another One (IRE) 10 Ms Caroline Ahearn John McConnell Ireland
Good Boy Bobby (IRE) 9 Mr Simon Munir & Mr Isaac Souede Nigel Twiston-Davies
Gwencily Berbas (FR) 11 Mr Aidan J Ryan David Pipe
Highland Hunter (IRE) 9 Mr T Barr Paul Nicholls
Hill Sixteen 9 J Fyffe & S Townshend Sandy Thomson
Itchy Feet (FR) 8 Kate & Andrew Brooks Olly Murphy
Jerrysback (IRE) 10 Mr John P McManus Philip Hobbs
Jett (IRE) 11 Mr Robert Waley-Cohen Olly Murphy
Kalooki (GER) 8 Mr Andrew L Cohen Philip Hobbs
Kapcorse (FR) 9 Mr John P McManus Paul Nicholls
Kauto Riko (FR) 11 Mr and Mrs J Dale and Partners Tom Gretton
Kildisart (IRE) 10 Mr Simon Munir & Mr Isaac Souede Ben Pauling
Larry 9 Galloping On The South Downs Partnership Gary Moore
Longhouse Poet (IRE) 8 Sean & Bernardine Mulryan Martin Brassil Ireland
Lord du Mesnil (FR) 9 Mr Paul Porter & Mike & Mandy Smith Richard Hobson
Lostintranslation (IRE) 10 Taylor & O'Dwyer Colin Tizzard
Mac Tottie 9 Steve & Jackie Fleetham Peter Bowen
Melon 10 Mrs J Donnelly Willie Mullins Ireland
Mighty Thunder 9 Allson Sparkle Ltd Lucinda Russell
Milan Native (IRE) 9 Gigginstown House Stud Gordon Elliott Ireland
Minella Times (IRE) 9 Mr John P McManus Henry de Bromhead Ireland
Mister Fogpatches (IRE) 8 Mr JB Fahy Pat Fahy Ireland
Mister Whitaker (IRE) 10 Mr TG Leslie Donald McCain
Mortal (IRE) 10 Mr A. Dunlop Gordon Elliott Ireland
Mount Ida (IRE) 8 KTDA Racing Gordon Elliott Ireland
Noble Yeats (IRE) 7 Mr P Byrne Emmet Mullins Ireland
Off You Go (IRE) 9 Mr John P McManus Charles Byrnes Ireland
Ontheropes (IRE) 8 Cheveley Park Stud Willie Mullins Ireland
Phoenix Way (IRE) 9 Mr John P McManus Harry Fry
Pink Eyed Pedro 11 Mr David Brace David Brace
Plan of Attack (IRE) 9 Mr A. Halsall Henry de Bromhead Ireland
Poker Party (FR) 10 Robcour Henry de Bromhead Ireland
Potters Corner (IRE) 12 All Stars Sports, Davies & Racehorse Club Christian Williams
Robin des Foret (IRE) 12 The 119 Partnership John McConnell Ireland
Roi Mage (FR) 10 Mr D. G. Pryde Patrick Griffin Ireland
Romain de Senam (FR) 10 Judith Wilson David Pipe
Run Wild Fred (IRE) 8 Gigginstown House Stud Gordon Elliott Ireland
Sam Brown 10 Mr T. C. Frost Anthony Honeyball
Samcro (IRE) 10 Gigginstown House Stud Gordon Elliott Ireland
Santini 10 Mr & Mrs R Kelvin-Hughes Polly Gundry
School Boy Hours (IRE) 9 Mr John P McManus Noel Meade Ireland
Scoir Mear (IRE) 12 Mr John P McManus Thomas Mullins Ireland
Secret Reprieve (IRE) 8 Mr & Mrs William Rucker Evan Williams
Smoking Gun (IRE) 9 D Barnard, N Courtney, M Madden, Gin & G Gee's Gordon Elliott Ireland
Snow Leopardess 10 Andrew Fox-Pitt Charlie Longsdon
Stones And Roses (IRE) 8 P. Reilly/C. Reilly Willie Mullins Ireland
The Big Dog (IRE) 9 Damien J. Kelly/Colin Kelly Peter Fahey Ireland
The Hollow Ginge (IRE) 9 The Ginge Army Nigel Twiston-Davies
The Two Amigos 10 Bradley Partnership Nicky Martin
Tiger Roll (IRE) 12 Gigginstown House Stud Gordon Elliott Ireland
Time To Get Up (IRE) 9 Mr John P. McManus Jonjo O'Neill
Top Ville Ben (IRE) 10 Harbour Rose Partnership Philip Kirby
Two For Gold (IRE) 9 May We Never Be Found Out Partnership 2 Kim Bailey
Uisce Beatha (IRE) 9 The Has Been's Sophie Leech
Via Dolorosa (FR) 10 Judith Wilson David Pipe
Windsor Avenue (IRE) 10 Phil & Julie Martin Brian Ellison
107 entries, 53 Irish-trained