Four men are in custody following an alleged stabbing murder in Adelaide's CBD overnight.
Just after 2am, police and STAR Group officers were called to North Terrace after a man was found injured lying on the road.
When officers arrived, they found the man had multiple stab wounds to his chest.
He died soon after.
Police are guarding the Quest on Franklin Hotel in Franklin Street as investigations continue.
Detectives have searched the area, including in bins.
One man was taken by police from the hotel to the City Watch House.
North Terrace has reopened to traffic between West Terrace and Morphett Road after being closed for several hours.
However, North Terrace remains closed between Station Place and Frome Road for the Anzac Day march.
