The Eagles are already without Milton Williams on Sunday and will finish their Week 12 matchup against the Bills without Fletcher Cox.
The veteran defensive tackle was forced to exit with a little over 3:00 minutes remaining in the first half after suffering a groin injury.
Cox could walk off the field but was seen gingerly walking towards the locker room.
Injury Update: DT Fletcher Cox (groin) is questionable to return.
— Philadelphia Eagles (@Eagles) November 26, 2023
With Cox out, Philadelphia has Jalen Carter, Jordan Davis, Marlon Tuipulotu, and Moro Ojomo available, while Brandon Graham can also play inside.