Here we go again.
Christian McCaffrey suffered a knee injury on Sunday Night Football in Week 13 and the San Francisco 49ers announced Monday that he has a PCL injury. McCaffrey will now go on injured reserve and he’s expected to miss the rest of the regular season.
That would have left Jordan Mason as the next man up in San Francisco, but he has a high ankle sprain that will also land him on injured reserve. Mason will now miss at least the next four games.
Following the injuries to both McCaffrey and Mason, Isaac Guerendo is a top priority must-add on the fantasy football waiver wire this week.
Elsewhere on the fantasy front, Russell Wilson (43.1%) is gaining steam at quarterback, Adam Thielen (27.3%) is relevant at wide receiver again, and Will Dissly (32.9%) has a good tight end matchup against KC this week.
Today, though, we’re focusing on the running back position. We’ve put together a quick list of 12 running backs to consider on the fantasy football waiver wire going into Week 14.
Fantasy Football Running Back Waiver Wire Targets
1. RB Isaac Guerendo (1.3%): With McCaffrey and Mason both sidelined, it should be the Guerendo show down the stretch in San Francisco.
2. RB Chris Rodriguez (0.2%): The Commanders placed Austin Ekeler on injured reserve with a concussion, leaving Brian Robinson as their top RB. Robinson is not alone in the backfield, however, as Rodriguez had a big day on Sunday with 94 rushing yards and a touchdown. If Washington continues splitting RB touches, Rodriguez could be a gem off the waiver wire.
3. RB Kimani Vidal (10.7%): J.K. Dobbins (knee) was ruled out and then placed on injured reserve, which means he’ll miss at least the next four games. Gus Edwards seems to be the new RB1 for the Chargers, but Vidal was right behind him in carries on Sunday (six to four). He’s a sleeper.
4. RB Alexander Mattison (47.0%): Mattison and Zamir White were both sidelined on Sunday, leaving Ameer Abdullah and Sincere McCormick (0.1%) as the Raiders’ top RBs in Week 13. Mattison is worth picking up for once he returns. If Mattison and White remain sidelined, McCormick will be worth a look in deep leagues.
5. RB Tank Bigsby (32.5%): Coming out of the bye week, Travis Etienne led the Jaguars’ backfield with 13 carries for 46 yards, but Bigsby also got seven carries plus one target. Up next is a Titans defense that allows 120.1 rushing yards per game.
6-12. Handcuff running backs: Jonathon Brooks (47.6%), Tyler Allgeier (41.5%), Zach Charbonnet (50.9%), Blake Corum (14.2%), Ray Davis (11.4%), Trey Benson (24.1%) and Braelon Allen (22.0%).
49ers injury update is bad news for 2 star running backs https://t.co/fDpMiOLDso pic.twitter.com/URAWpw5Pik
— Niners Wire (@TheNinersWire) December 2, 2024
Roster percentages for players listed in this article were sourced from ESPN. For more fantasy coverage, check out our fantasy football hub.