Eating oily fish like mackerel or salmon could slash your risk of developing Alzheimer's disease by nearly 50 per cent, a new study has revealed. Scientists found that people with high levels of omega-3 DHA in their blood were at 49 per cent lower risk of getting the debilitating brain condition.
This was particularly true for those carrying the ApoE4 gene which doubles the chances of getting Alzheimer's. Study authors from the Fatty Acid Research Institute (FARI) in the US said their results could lead to a cheap, low-risk way to save billions in treatment.
The research took place within the Framingham Offspring Cohort and included 1,490 people aged 65 or over who did not have Alzheimer's. Researchers examined the association of red blood cell marine omega-3 docosahexaenoic acid (DHA) with Alzheimer’s Disease while also testing for an interaction with ApoE4 gene carriership.
There are three types of Omega-3, DHA and Eicosapentaenoic acid (EPA) both found particularly in oily fish, and alpha-linolenic acid (ALA) found in plants which is not as good for you. The study said that providing extra dietary Omega-3 DHA could slow the onset of the disease.
If those with the the lowest levels were to reach those with the highest, they would gain an extra 4.7 years free of Alzheimer's. Study author Dr Aleix Sala-Vila said: "The risk for Alzheimer's disease in the highest DHA fifth was 49% lower compared with the lowest fifth.
"Delaying Alzheimer's disease by five years leads to 2.7 additional years of life, and 4.8 additional Alzheimer-free years for an individual who would have acquired Alzheimer's." Although only observational, the findings published in the journal Nutrients stand up similar findings in the original Framingham Heart Study 15 years ago.
President of FARI, and senior author Dr William Harris, said: “Most interestingly, 15 years ago similar findings were reported in the parents of the individuals who were the focus of this present investigation with a 47 per cent in the risk of developing all-cause dementia. Similar findings a generation apart in a similar genetic pool provide considerable confirmation of this DHA-dementia relationship.”
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