![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_18891964_168393153_lowres.jpg?w=1000&h=600&crop=1)
The Eagles are about eight hours away from kicking off a road matchup against Zach Ertz, Kyler Murray, and the Arizona Cardinals.
The Birds are a slight favorite and will look to start the season 5-0, with a matchup against the Cowboys looming in Week 6.
Jalen Hurts continues to cement his status and a new contract this season.
At the same time, Jonathan Gannon’s retooled defense will look to continue its strong play.
With the team settled in and prepared, here’s an updated look at the 53-man roster with news and notes.
#1 QB Jalen Hurts
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_15345479_168393153_lowres.jpg)
Hurts will dual with Kyler Murray for the second time in his NFL career.
#2 CB Darius Slay
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/e743a0e01f0d421cabd9d4c4ca36edf1.jpg)
The Eagles cornerback has dealt with a forearm injury, but he’ll play against Hollywood Brown.
#3 WR Zach Pascal
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/1427318451.jpg)
#4 K Jake Elliott
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19165921_168393153_lowres.jpg)
Philadelphia’s Pro Bowl kicker has been ruled out with an ankle injury.
#6 WR Devonta Smith
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/1427318581.jpg)
#7 LB Haason Reddick
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19164687_168393153_lowres-2.jpg)
Reddick is the reigning Defensive Player of the Week after a two-sack performance against the Jaguars.
#8 P Arryn Siposs
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2021/09/Arryn-Siposs-e1630541854706.jpg)
#10 QB Gardner Minshew
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/USATSI_19114813_168393153_lowres.jpg)
#11 WR A.J. Brown
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19164816_168393153_lowres.jpg)
Brown currently sits in the top three for receiving yards in the NFL, with over 400 yards.
#14 RB Kenneth Gainwell
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19166025_168393153_lowres.jpg)
Gainwell scored a ten-yard touchdown in Philadelphia’s win over Jacksonville.
#16 WR Quez Watkins
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/USATSI_19079440_168393153_lowres-2.jpg)
Watkins has been held without a catch in two straight games.
#17 LB Nakobe Dean
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/1416630848.jpg)
The talented rookie has seen all his game action on special teams.
#18 WR Britain Covey
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/e2d8f4eecd274595942c9368b76d2658.jpg)
The undrafted rookie will handle duties in the return game.
#19 QB Ian Book
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/50c51afad9904227b751a916dc62810a.jpg)
Book will likely be inactive for his fifth straight game.
#22 S Marcus Epps
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/73108a65f7c74804a6ce725ed3c99827.jpg)
#23 S C.J. Gardner-Johnson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/1429714950.jpg)
#24 CB James Bradberry
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19165646_168393153_lowres.jpg)
#26 RB Miles Sanders
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19164084_168393153_lowres-3.jpg)
Sanders sits among the top three in rushing yards and is clearly on pace for his first 1,000-yard rushing season.
#27 CB Zech McPhearson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/1416499031.jpg)
#28 CB Josh Jobe
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/0ad07c352d454e318068a952daa70cab-1.jpg)
#29 CB Avonte Maddox
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/9fd1e534758d436aa2fe4fdcb750a1d0.jpg)
The slot cornerback will miss his second straight game with an ankle injury.
#32 S Reed Blankenship
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/a6d6f696cd314daf9cd5b6c2f1b95ab5-e1662326188871.jpg)
#33 CB Josiah Scott
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/1429706364.jpg)
Scott will start in the slot with Avonte Maddox ruled out.
#34 RB Trey Sermon
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/1429703063.jpg)
The hard running Sermon saw his first game action against the Jaguars last week.
#35 RB Boston Scott
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/62668ad1e827466fad318ec657d006a5.jpg)
#42 S K'Von Wallace
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/1425379565.jpg)
#43 LB Kyzir White
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/1427306052.jpg)
White will play a key role in containing Zach Ertz.
#45 LS Rick Lovato
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/USATSI_18907468_168393153_lowres.jpg)
#48 LB Patrick Johnson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/USATSI_18940466_168393153_lowres.jpg)
#51 C Cam Jurgens
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/USATSI_18880121_168393153_lowres.jpg)
#54 LB Shaun Bradley
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/USATSI_17068752_168393153_lowres.jpg)
#55 DE Brandon Graham
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/1427292073-1.jpg)
#56 OL Isaac Seumalo
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/USATSI_19093839_168393153_lowres.jpg)
#57 LB T.J. Edwards
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/1429714051.jpg)
#58 LB Kyron Johnson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/05/7a13b5161b56495387d769da10621f91.jpg)
Johnson cleared the concussion protocol and will be available for his special team’s role.
#59 DE Janarius Robinson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/b29663f659e54a1fa0790aaf2f1e53ba.jpg)
#61 C Josh Sills
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/a38ac16b9ff944f98c45295ef66bcf25-1.jpg)
#62 C Jason Kelce
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/USATSI_19093855_168393153_lowres.jpg)
#63 OL Jack Driscoll
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/1123f6d4cc444a0295d31600a601e724.jpg)
Driscoll will start at left tackle for injured Jordan Mailata.
#65 RT Lane Johnson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19165787_168393153_lowres.jpg)
#68 LT Jordan Mailata
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19093820_168393153_lowres.jpg)
Mailata will miss the matchup with a separated shoulder.
#69 LG Landon Dickerson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/USATSI_19093814_168393153_lowres.jpg)
#75 DE Tarron Jackson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/1416607701.jpg)
#78 OL Sua Opeta
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2021/12/Sua-Opeta-Eagles-53-man-roster.jpg)
#81 TE Grant Calcaterra
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19141468_168393153_lowres.jpg)
#88 TE Dallas Goedert
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19164802_168393153_lowres.jpg)
#89 TE Jack Stoll
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/1427318044.jpg)
#90 DT Jordan Davis
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19165971_168393153_lowres.jpg)
#91 DT Fletcher Cox
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19164813_168393153_lowres.jpg)
#93 DT Milton Williams
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2021/10/Milton-Williams-Chiefs.jpg)
#94 DE Josh Sweat
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19170938_168393153_lowres.jpg)
#95 DT Marlon Tuipulotu
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/08/1d71ca9eaa024c4185fffee730afbf8a-e1661208602531.jpg)
#97 DT Javon Hargrave
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/1427318602.jpg)