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The Eagles are set to depart for Indianapolis for a Week 11 matchup against the Colts that offers familiar storylines and a recipe for disaster.
Philadelphia was just dominated up front in a loss to the Commanders, and they’ll face an improving run offense that features a now healthy Jonathan Taylor at running back.
Both teams feature dynamic players on defense, and we’re previewing 15 impact players to watch.
1
Michael Pittman
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19427992_168393153_lowres.jpg)
Pittman leads the Colts with 61 catches on 89 targets for 603 yards and one touchdown. A physical wide receiver, he could cause problems for Darius Slay.
2
A.J. Brown
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/10/USATSI_19330065_168393153_lowres-2.jpg)
Brown will look to bounce back from a one-catch, seven-yard performance in the loss to Washington, and he’ll likely draw Stephon Gilmore.
3
Quenton Nelson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19165955_168393153_lowres.jpg)
4
Landon Dickerson
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/09/USATSI_19093814_168393153_lowres.jpg)
A future All-Pro at left guard, Dickerson will have his hands full with Buckner.
5
Kenny Moore II
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19332997_168393153_lowres.jpg)
A Pro Bowl cornerback, Moore is tied for fourth in total tackles with Rodney McLeod (51).
6
Jack Stoll
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19380856_168393153_lowres.jpg)
The former Nebraska tight end is a solid player, and he’ll get the first shot at replacing an injured Dallas Goedert.
Undrafted out of Nebraska, Stoll has been known for his prowess as an in-line blocker, but he’s also an improved pass catcher as well.
7
Jonathan Taylor
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19428437_168393153_lowres.jpg)
Taylor missed three games this season because of injury, but he’s rebounded and exploded against the Raiders.
Despite missing three games, Taylor has logged 609 yards on 129 carries.
8
Miles Sanders
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/1441511746.jpg)
Sanders has 710 yards rushing on the season and will likely see a significant workload as both teams work to keep the opposition’s explosive offense on the sideline.
9
Dayo Odeyingbo
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19165257_168393153_lowres.jpg)
with Kwity Paye ruled out, Odeyingbo will be the primary pass rusher for the Colts.
10
Josh Sweat
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/1441530718.jpg)
Sweat is the Eagles’ best pass rusher and will be heavily involved in making Matt Ryan uncomfortable in the pocket.
11
DeForest Buckner
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19429804_168393153_lowres.jpg)
The massive defensive tackle will be a player to watch in the middle of the Colts’ injury-riddled defense.
Buckner was able to log a full practice on Thursday and should be available.
The All-Pro has recorded 43 tackles, 5.5 sacks, and two passes defended over the first ten games of the season.
12
Linval Joseph
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_17444862_168393153_lowres.jpg)
A professional run stopper who embraces eating up space, Joseph should see about ten to 12 snaps on Sunday in obvious running situations.
13
Rodney McLeod Jr.
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19331627_168393153_lowres.jpg)
The former Eagles safety started training camp as a backup but eventually secured the starting job and logged 33 tackles, one interception, and three passes defended.
McLeod spent six years in Philadelphia and played a considerable role in Marcus Epps’s development into a starter.
14
Stephon Gilmore
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19430156_168393153_lowres.jpg)
One of the top cornerbacks to enter the NFL in the past decade, Gilmore had his issues with Terry McLaurin a few weeks ago and will likely draw A.J. Brown in a high-profile matchup.
15
Darius Slay
![](https://theeagleswire.usatoday.com/wp-content/uploads/sites/69/2022/11/USATSI_19434900_168393153_lowres-1-1.jpg)
With Philadelphia expected to stack the box in the hope of slowing down Colts running back Jonathan Taylor, it’ll be Slay traveling with the Colts’ top pass catcher.