Dunnes Stores took no chances with their decision ahead of the Cork anti-lockdown protest on Saturday.
They along with some other shops boarded up windows as a crowd of several hundred gathered on Patrick Street in Cork.
Six people were arrested in connection with the demonstration against lockdown restrictions.
The gathering in Cork city centre passed off without major incident on Saturday afternoon.
Peter posted on Twitter: "Dunnes Stores not taking any chances."
Niamh posted: "Some store owners in Cork has taken it upon themselves to board up their shops for the day. Pictured below is Dunnes Stores."
Jon Seward said: "Dunnes Stores taking no chances ahead of todays Anti-Lockdown protest assembly in Cork City ."
A similar event ended in violent scenes in the capital Dublin last weekend.
Public gatherings are currently banned under the coronavirus regulations.
Garda said more than 200 officers were involved in Saturday's policing operation.
Two men were arrested in Cork city, one for a breach of coronavirus regulations and the other for public order offences.
Checkpoints were carried out by Garda on routes to Cork, and organisers have claimed that some who had been planning to attend the demonstration were turned back.
Garda said four arrests were made linked to the event in Cork.
Three men and one woman were arrested in Kildare, Kerry and County Cork for failing to comply with Garda directions.
There had been pleas to call off the event, including by the city's Lord Mayor Joe Kavanagh and government minister Simon Coveney.
Demonstration organisers the People's Convention said it would be a "peaceful assembly".
Speeches were heard by participants carrying banners, some of which read "Tell the Truth" and "Freedom Not Tyranny".
It ended with the singing of the National Anthem.
Last weekend in Dublin, there were chaotic scenes at an anti lockdown protest, and 23 arrests were made as well as three Garda officers injured.
