Prime Video's adult animated series, 'The Second Best Hospital in the Galaxy,' brings together all five Culkin brothers for the first time, with Kieran Culkin voicing one of the main characters, Dr. Plowp. The show's executive producer and co-star, Natasha Lyonne, played a pivotal role in making this collaboration happen. Kieran's suggestion to involve his brothers in the project led to a unique twist in the storyline, aligning perfectly with the character dynamics.
The series also features the talents of Maya Rudolph, who not only voiced a character but also served as an executive producer. The casting process for the lead roles of the two brilliant female alien doctors involved analyzing interviews from YouTube talk shows to ensure a seamless fit between the actresses, Stephanie Hsu and Keke Palmer.
Due to the challenges posed by the COVID-19 pandemic, the stars recorded their parts separately but managed to create a cohesive performance by playing off each other's playback audio. Hsu and Palmer expressed their excitement at the opportunity to work together, despite not physically sharing the same space during recording.
'The Second Best Hospital in the Galaxy' marks another successful collaboration between Rudolph and Lyonne under their Animal Pictures producing banner. However, the duo recently announced an amicable decision to pursue individual projects moving forward, with both actresses looking forward to exploring new creative ventures.
The series, set to premiere on Prime Video, promises a unique blend of humor, sci-fi elements, and stellar performances from the talented ensemble cast. Fans can look forward to experiencing the magic of this animated show when it starts streaming on Friday.