Reece James has lost his fight to start today's London derby between Chelsea and Arsenal.
Mauricio Pochettino has named a team featuring Raheem Sterling in the central striker's role following injuries to Nicolas Jackson and Armando Broja.
Mykhailo Mudryk and Cole Palmer will flank Sterling in attack, the latter having overcome a knock suffered during the international period, while Malo Gusto is back from his ban to start at right-back.
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Chelsea suffered injury setbacks to Romeo Lavia, Carney Chukwuemeka and Trevoh Chalobah this week.
They join Broja, Christopher Nkunku, Wesley Fofana, Ben Chilwell and Marcus Bettinelli on the sidelines.
Striker Jackson had minor surgery on a wrist injury sustained against Brighton last month and faced a late fitness test.
Jackson, James and Axel Disasi are on the bench along with the returning Benoit Badiashile.
Enzo Fernandez and Moises Caicedo are ready to play despite returning from South America on Wednesday evening following their international fixtures for Argentina and Ecuador.
Chelsea XI: Sanchez; Gusto, Thiago Silva, Colwill, Cucurella; Fernandez, Caicedo, Gallagher; Palmer, Sterling, Mudryk
Subs: Petrovic, Badiashile, James, Disasi, Maatsen, Ugochukwu, Madueke, Washington, Jackson
Injuries: Bettinelli, Fofana, Chalobah, Chilwell, Chukwuemeka, Lavia, Nkunku, Broja
Time and date: 5.30pm BST on Saturday, October 21, 2023
Location: Stamford Bridge, London