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Chelsea have been hit with injuries to Trevoh Chalobah and Robert Sanchez ahead of a return to Premier League action.
Chalobah has started for Chelsea ar centre-back in their last four matches since the Carabao Cup Final defeat to Liverpool at Wembley.
He has started to form a partnership with Axel Disasi and his injury is another setback for Mauricio Pochettino.
Chelsea are already without Levi Colwill and Pochettino will be forced to recall either Thiago Silva or Benoit Badiashile at the heart of the Chelsea defence.
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Backup goalkeeper Sanchez and Carney Chukwuemeka have also been added to the injury list at Stamford Bridge.
Chukwuemeka withdrew from the England Under-21 squad this week to return to Cobham for treatment.
Christopher Nkunku remains sidelined, while Romeo Lavia has been ruled out for the rest of the season as the injury problems mount for Pochettino.
Reece James and Wesley Fofana are long-term absentees.
Chelsea face Burnley as they bid to start the run-in on a positive note and finish the season strongly.
The Blues are still languishing in the bottom half of the Premier League table.