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Benzinga
Benzinga
Technology
Vandana Singh

Checkmate Pharma Shares Skyrocket Over 300% On Regeneron $250M Acquisition Deal

  • Regeneron Pharmaceuticals Inc (NASDAQ:REGN) will acquire Checkmate Pharmaceuticals Inc (NASDAQ:CMPI) for $10.50 per share, equivalent to a total equity value of approximately $250 million.
  • Checkmate is a clinical-stage biopharmaceutical company focused on proprietary technology to harness the immune system's power to combat cancer.
  • The offer price represents a whopping premium of over 300% on Monday's last close price of $2.41.
  • Checkmate's lead investigational candidate is vidutolimod, an advanced generation CpG-A oligodeoxynucleotide Toll-like receptor 9 (TLR9) agonist delivered in a virus-like particle.
  • Vidutolimod is administered into the tumor and is believed to induce and expand anti-tumor T cells and tumor regression as a monotherapy in patients whose tumors previously progressed on PD-1 checkpoint inhibition. 
  • The transaction is expected to close in mid-2022.
  • Patient dosing was initiated in a Phase 2 study evaluating vidutolimod combined with cemiplimab, supported by a clinical collaboration with Regeneron.
  • Cohorts focused on anti-PD-1 refractory cutaneous squamous cell carcinoma, and Merkel cell carcinoma are currently enrolling.
  • The Company expects preliminary data from the Phase 2 head & neck cancer trial on a subset of patients and Phase 2 non-melanoma skin cancer trial cohorts in 2H of 2022.
  • Regeneron held a cash balance of $12.5 billion at the end of 2021.
  • Price Action: CMPI shares are trading 332.4% higher at $10.42 during the premarket session on the last check Tuesday.
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