For Ange Postecoglou the Scottish Premiership title is within touching distance.
A win over Rangers will Celtic nine points clear with a far superior goal difference going into the final three fixtures.
But ahead of kick-off the Australian has some big decisions to make over his starting line-up at Celtic Park.
Midfielder Nir Bitton will be available having returned to training following a fitness issue.
His derby day experience could be vital, and he could offer support to the defence against a the prospect of a Rangers front two amid the absence of Alfredo Morelos and Kemar Roofe.
Josip Juranovic remains on the sidelines with the injury he picked up in the recent Scottish Cup defeat at Hampden.
Kyogo Furuhashi and Giorgios Giakoumakis are dominating the debate among fans with one set to be given the nod to lead the line.
Predicted Celtic XI
Nir Bitton looks set to return to the side and could play the holding role in the midfield, freeing up captain Callum McGregor against Rangers.
Anthony Ralston is the obvious choice at right-back in the absence of Josip Juranovic.
With Kyogo struggling to make an impact at Hampden, Postecoglou could go with Giorgios Giakoumakis as he key frontman.
Provisional Celtic squad
Vasilis Barkas
Joe Hart
Scott Bain
Christopher Jullien
Stephen Welsh
Dane Murray
Greg Taylor
Carl Starfelt
Liam Scales
Nir Bitton
Callum McGregor
Giorgos Giakoumakis
Liel Abada
Ismaila Soro
Tom Rogic
Karamoko Dembele
Yousuke Ideguchi
Matt O'Riley
David Turnbull
Anthony Ralston
James McCarthy
Jota
Mikey Johnston
Cameron Carter-Vickers
Reo Hatate
Daizen Maeda
Kyogo Furuhashi
James Forrest