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Wales captain Ken Owens has been ruled out of their World Cup training squad due to injury.
The hooker has been released from the squad with a back injury along with Scarlets team-mate Josh Macleod who has a shoulder problem.
Cardiff’s Will Davies-King has also been ruled out with a foot injury, while Alun Wyn Jones, Justin Tipuric and Rhys Webb have all retired since the preliminary squad was released last month.
Ospreys hooker Sam Parry has been called up ahead of the World Cup, where Wales’ campaign gets under way against Fiji on September 10 followed by games against Australia and Georgia.
Head coach Warren Gatland said: “We’ve been really pleased with the players’ attitude and commitment throughout the first few weeks of our mini camps.
“The group has worked really hard and there have been a few curve balls from us in terms of testing them mentally and physically as people may have seen in some of our videos.
“Unfortunately we’re having to release Ken, Josh and Will due to injury which is really disappointing, but all three are hoping to be available later in the year should we need an injury replacement at any point.
“Ken has a niggle in his back which he needs some time out to sort. Josh got the injury on club duty – we were hoping to be able to manage it but specialist assessment showed that wasn’t possible.
“Will picked up the foot injury in training with us which we were managing but then he got re-injured so has been released.”