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Liverpool Echo
Liverpool Echo
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Fiona Callingham & Olivia Williams

Bowel cancer warning signs which can show up two years before diagnosis

There are number of warning signs of bowel cancer which researchers said can show two years before diagnosis.

Bowel cancer is the fourth most common type of cancer in the UK, with around 43,000 new cases every year, according to Cancer Research UK. A new study identified four "red flag" bowel cancer symptoms, which can be seen in patients under 50, months before diagnosis, reports the Express.

The disease is the second most deadly, causing almost 17,000 deaths a year and accounts for around 11% of all new cancer cases. More than half of bowel cancer cases (54%) in the UK are thought to be preventable.

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While there are many symptoms to watch out for, new research has found key warning signs that could indicate greater risk of early-onset bowel cancer - that is, occurring under the age of 50. Researchers said patients were likely to experience four symptoms between three months and two years before diagnoses

It was determined that having just one of the symptoms almost doubled the risk for bowel cancer. Those who had two symptoms were more than three and a half times at risk; and having three or more symptoms increased the risk by more than six and a half times.

These 'red flag' symptoms were:

  • Abdominal pain
  • Rectal bleeding
  • Diarrhoea
  • Iron deficiency anaemia

Researchers from the Washington University School of Medicine in St Louis believe these red flags may help with earlier detection and diagnosis among younger adults. The study, published in the Journal of the National Cancer Institute, analysed data on more than 5,000 patients with early-onset bowel cancer.

Senior investigator Yin Cao explained: "Colorectal cancer is not simply a disease affecting older people; we want younger adults to be aware of and act on these potentially very telling signs and symptoms - particularly because people under 50 are considered to be at low risk, and they don’t receive routine colorectal cancer screening.

"It's also crucial to spread awareness among primary care doctors, gastroenterologists and emergency medicine doctors. To date, many early-onset colorectal cancers are detected in emergency rooms, and there often are significant diagnostic delays with this cancer.”

Bowel cancer screening in the UK is currently offered to people aged between 60 and 74 every two years, but the programme has been gradually expanding since 2021 to include people aged 50 to 59. Dr Cao added that two symptoms in particular - rectal bleeding and iron deficiency anaemia - called for timely endoscopy and follow-up.

First study author Cassandra Fritz said: "It usually takes about three months to get a diagnosis from the time a person first goes to the doctor with one or more of the red flag signs and symptoms we’ve identified. But in this analysis, we found that some young adults had symptoms for up to two years prior to their diagnoses.

"That may be part of the reason many of these younger patients had more advanced disease at the time of diagnosis than what we normally see in older people who get screened regularly." While the US study highlighted some key red flags, there are a number of symptoms which could indicate bowel cancer.

According to the NHS, the main symptoms include:

  • Changes in your poo, such as having softer poo, diarrhoea or constipation that is not usual for you
  • Needing to poo more or less often than usual for you
  • Blood in your poo, which may look red or black
  • Bleeding from your bottom
  • Often feeling like you need to poo, even if you've just been to the toilet
  • Tummy pain
  • Bloating
  • Losing weight without trying
  • Feeling very tired for no reason.

The NHS advises you see a GP if you have any symptoms of bowel cancer for three weeks or more. Some of the symptoms listed are very common and can be caused by other conditions, so they don't necessarily mean you have bowel cancer - but you should still get checked by a GP.

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