A car has been driven into a crowd of people with at least one dead and multiple injured with the drama being witnessed by TV's John Barrowman.
A driver, 29, with dual German-Armenian citizenship, rammed a small silver Renault Clio into a crowd on the corner of Rankestrasse before smashing into a shop window 200 metres away in Charlottenburg, Berlin, Germany.
Berlin Police said around 130 emergency responders including an air ambulance unit are taking care of the injured at the scene and that they have secured a "small car".
They added: "There are several injured, some seriously, and according to the current status, one dead person."
Nothing is yet known about the driver, but police have confirmed he is in custody.
Police at first said there was 30 injured - they now say there is around dozen hurt.
There are five with life-threatening injuries, the fire service confirmed.
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Images from the scene show chairs and tables scattered outside a department store and a small Renault with Berlin license plates parked in a shop window.
Others show emergency services working frantically on the injured in the street.
Unconfirmed reports allege the fatal victim was a teacher who was in the area as part of a group outing.
Berlin Police confirmed the driver's age and nationality with SkyNews.
Doctor Who and Dancing on Ice star Mr Barrowman, who witnessed the incident, told his Twitter followers: "We think we have witnessed a terrorist attack here in Berlin we’re not sure there’s a lot of people dead bodies all over the place we’ve seen a car that came down the road and ended up in a storefront covering three city blocks it’s pretty horrific. #berlin."
In a video, Mr Barrowman described the situation as "really bad" and said he hid behind a tree to protect himself in case of another attack.
Describing the scene, he said there was a huge emergency response and he could see a dead person laying in the middle of the street.
In another update 15 minutes later, he said he saw "multiple fatalities".
Investigators were looking into whether the incident was a deliberate attack or possibly an accident with a medical cause, a police spokesperson said.
Blankets covered what appeared to be a body in a cordoned-off area guarded by police, Reuters images showed.
A small, silver coloured Renault car was lodged inside a shop after smashing through a plate glass window.
The incident took place next to the war-ravaged Gedaechtniskirche church, one of Berlin's best-known landmarks.
Rescue workers moved apparently conscious people on stretchers towards an ambulance, including one woman sitting up, and another who covered her face with her hand, Reuters images showed.
Mr Barrowman told Sky News: "I saw a woman being put into an ambulance ... it looked like they were resuscitating somebody."
The site, on a shopping street near a McDonald's restaurant, was cordoned off. Bystanders looked up at a helicopter circling above.
German police confirmed the male suspect is now in custody and that he had received some medical treatment.
They told Tages Spiegel: "We do not yet know whether it was an intentional act or a traffic accident.
"We arrested the driver and are clarifying the matter."
A spokesperson for the German capital's fire service said: "A man is believed to have driven into a group of people."
The incident took place near the site of a fatal attack in 2016 when Anis Amri, a failed Tunisian asylum seeker with Islamist links, hijacked a truck, killed the driver and then ploughed it into a crowded western Berlin Christmas market, killing 11 more people and injuring dozens of others.
The 24-year-old had been asked to show his identity documents by police before pulling out a pistol who then returned fire hitting the suspect in the chest.
Security officials later confirmed "without any shadow of a doubt" that the dead man is Amri after identifying him using his fingerprints.
Berlin's Governing Mayor Franziska Giffey (SPD) was "deeply affected by this terrible event". She thanked the emergency services for their work on site and expressed her condolences to the victims and their families. Giffey avoided any statement about the background of the incident and explained: "It's about clarifying what happened and what happened."
Interior Senator Iris Spranger said on Twitter on Wednesday: "I am shocked by the incident in Charlottenburg. I am in the situation center and keep myself informed. My thoughts and my deepest sympathy are with all those affected."
