Labor says voters can expect to see a "team" effort while leader Anthony Albanese isolates after testing positive for COVID-19.
Campaign spokesman Jason Clare says Mr Albanese's diagnosis provides an opportunity for Labor to showcase its united team ahead of polling day.
Mr Clare says there will not be a de facto opposition leader during the course of Mr Albanese's isolation, even though Labor has a deputy leader Richard Marles.
"We're not a one-man band. We're a strong united team and we'll show that over the course of the next few days," Mr Clare told reporters in Sydney.
"I see this as an opportunity ... because not only have we got a better plan, we've got a better team."
The Labor leader returned a positive result following a routine PCR test on Thursday afternoon.
Mr Albanese was due to fly out on Friday from Sydney to campaign in Western Australia but will instead isolate at his Sydney home for seven days.
"While at home I will continue my responsibilities as alternative prime minister and will be fighting for a better future for all Australians," Mr Albanese said in a statement.
Prime Minister Scott Morrison wished Mr Albanese well, saying 50,000 Australians catch the virus every day and continue on with their lives.
"You just get on with it," Mr Morrison told the Seven Network.
"When I had COVID ... we had Quad meetings, major presentations and I'm sure (Mr Albanese) will be able to do that from his home in Sydney.
"Hopefully the symptoms aren't too bad but I wish him a speedy recovery."
Senior Nationals senator Bridget McKenzie said "the stakes are very high at the moment" when asked whether the coalition has an advantage.
"We've got a strong campaign and a strong proposition for the Australian people," she told the ABC.
Labor campaign heads had prepared for the possibility Mr Albanese might test positive.
ALP national president Wayne Swan said Labor had "war-gamed for this".
"There's an enormous amount that Albo can do from isolation. We've got a really talented frontbench team that can be on the job and out in the public," he told the Nine Network.
"We will continue to hold the government to account on its negligence, particularly in terms of foreign policy and defence, but we'll also continue to outline our policies for the future."
Labor's campaign launch, set down for May 1 in Perth, is expected to go ahead as planned.
A senior frontbencher will take the travelling press pack to marginal Sydney seats on Friday as Labor combats the coalition's attacks over national security.
Mr Morrison started the Friday morning media rounds by accusing the opposition of being weak on China, following a security pact being signed by the Solomon Islands.
"This is about the actions of the Chinese government seeking to impose influence in our region, which is against not only our national security interests but frankly, the security interests of all Pacific nations," he told 4BC.
"There is a lot of concern about this. And what I find just galling is that the Labor Party were attacking us over this issue."
But Mr Clare targeted the government for failing to stop the Chinese security deal, saying the Morrison government had been "sitting on their hands" while Beijing expanded its influence.
"You can't sit back on the deck chair in the Pacific and assume that everything's going to be okay," he said.
"If China is in there trying to set up a security agreement, then you expect that Canberra would be doing something about it."
Mr Morrison is in Queensland on Friday, where he will announce a $428 million upgrade to four defence force air bases.
Construction at Amberley, Richmond, Pearce and HMAS Albatross would create 600 new jobs, with the upgrades to be completed by 2024.
