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A Ukrainian maternity hospital has been hit in an air strike. Here's what we know so far

It's understood some women were in labour when this hospital was hit. (AP: Evgeniy Maloletka)

A maternity and children's hospital has been significantly damaged in an air strike in Ukraine.

The hospital is in the besieged port city of Mariupol in Ukraine's south-east, not far from the Russian border.

The number of casualties is still to be determined, with authorities searching through dangerous rubble for survivors.

Here's what we know about the incident so far.

What happened at the maternity hospital?

The medical complex was hit by a series of blasts, with significant damage caused to almost the entire front of the maternity hospital building.

Map of Ukraine showing location of Mariupol Children’s Hospital. (ABC News)

Confronting images have emerged of heavily pregnant women and mothers with young children being evacuated from the site, including on stretchers.

Reports from Ukraine say the blasts shook the ground well over a kilometre from the hospital.

They also left a large crater and caused windows in buildings to shatter.

Nearby, other buildings, cars and trees caught fire.

How many people were hurt?

Ukrainian officials say at least 17 people have been injured, but that number is likely to rise.

Ukrainian President Volodymyr Zelenskyy says there are "people [and] children under the wreckage", and MP Dmytro Gurin tweeted that "a lot" of women had been killed.

It is not known at this stage whether any unborn children of expectant mothers who were at the hospital during the strike have been hurt or killed.

The UN's Human Rights body says it is still verifying the number of casualties.

Spokesperson Liz Throssell said in a statement the incident "adds to our deep concerns about indiscriminate use of weapons in populated areas and civilians trapped in active hostilities". 

It's still unclear how many people were hurt in the attack. (AP: Evgeniy Maloletka)

What happened after the strike?

Authorities are continuing to search for survivors in the rubble.

And Ukrainian authorities are saying Russia has backflipped on its commitment to a ceasefire in Mariupol to allow civilians to evacuate.

ABC correspondent Sean Rubinsztein-Dunlop says the people of Mariupol have been trapped by Russian bombs for days and many have no access to power, water or food.

English teacher turned soldier speaks from the frontline in Kyiv.

What has Ukraine said so far?

Mr Zelenskyy has called the incident an "atrocity" and shared confronting footage from the hospital.

He called it a "direct strike of Russian troops". 

Regional police official Volodymir Nikulin spoke briefly from the site of the air strike, saying Russia had "committed a huge crime".

"It is a war crime without any justification," he said.

Ukraine's Vice-Prime Minister, Mykhailo Fedorov, said the strike was carried out by "Russian murderers".

Has Russia commented?

Russia has repeatedly denied targeting civilians during its invasion. However, Ukraine says hundreds of people, including children, have been killed and civilian infrastructure has been attacked.

A Kremlin spokesperson has reportedly blamed Ukraine for the failure of a planned evacuation from Mariupol, reiterating that Russian forces "do not fire on civilian targets".

Mr Zelenskyy spoke briefly in Russian during his nightly video address, asking how a maternity and children's hospital could possibly be seen as a threat to the Russian Federation.

"What kind of country is this, the Russian Federation, which is afraid of hospitals, afraid of maternity hospitals, and destroys them?" he said.

Aid agencies say refugees are dying from extreme cold at Polish border (Anne Barker)

ABC/wires

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