The 49ers on Friday ruled out cornerback AJ Parker and wide receiver Chris Conley late in the third quarter.
Both players were on the roster bubble entering Friday night’s preseason finale.
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Conley is ruled out with a shoulder injury he appeared to sustain on a 34-yard diving catch in the second quarter.
Parker has a hamstring injury he suffered while covering a punt late in the first half.
The severity of the injuries is unclear, but any kind of long-term issue could impact whether they wind up making the initial 53-man roster.
